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Простое начало. Как четыре закона физики формируют живой мир - Партасарати Рагувир

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1 Potten C. S., Morris R. J. Epithelial stem cells in vivo. J. Cell Sci. 1988; 45–62. Считают, что в день теряется около 1011 клеток при массе каждой около 11–12 килограммов, а это соответствует потере около 3 тысяч килограммов в течение жизни.

2 Engler J. et al. Matrix elasticity directs stem cell lineage specification. Cell. 2006; 126: 677–689.

3 Keung J. et al. Presentation counts: Microenvironmental regulation of stem cells by biophysical and material cues. Annual Review of Cell and Developmental Biology. 2010; 26: 533–556.

4 Haswell E. S. et al. Mechanosensitive channels: What can they do and how do they do it? Structure. 2011; 19: 1356–1369; Peyronnet R. et al. Mechanosensitive channels: Feeling tension in a world under pressure. Front. Plant Sci. 2014; 5: 558.

5 Aragona M. et al. Mechanisms of stretch-mediated skin expansion at single-cell resolution. Nature. 2020; 584: 268–273.

6 Yamamoto K. et al. Fluid shear stress induces differentiation of Flk-1-positive embryonic stem cells into vascular endothelial cells in vitro. American Journal of Physiology-Heart and Circulatory Physiology. 2005; 288: H1915 – H1924 (2005); Wang H. et al. Shear stress induces endothelial differentiation from a murine embryonic mesenchymal progenitor cell line. Arteriosclerosis, Thrombosis, and Vascular Biology. 2005; 25: 1817–1823.

7 Landecker H. Culturing Life: How Cells Became Technologies. Cambridge, MA: Harvard University Press, 2010; Steinberg M. S., Takeichi M. Experimental specification of cell sorting, tissue spreading, and specific spatial patterning by quantitative differences in cadherin expression. Proc. Natl. Acad. Sci. 1994; 91: 206–209.

8 Simian M., Bissell M. J. Organoids: A historical perspective of thinking in three dimensions. J. Cell Biol. 2017; 216: 31–40.

9 Sato T. et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature. 2009; 459: 262–265.

10 Eiraku M. et al. Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature. 2011; 472: 51–56.

11 Eiraku M. et al. Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals. Cell Stem Cell. 2008; 3: 519–532.

12 Lancaster M. A. et al. Cerebral organoids model human brain development and microcephaly. Nature. 2013; 501: 373–379.

13 Cepelewicz J. An ethical future for brain organoids takes shape. Quanta Magazine. 2020; January 13 (https://www.quantamagazine.org/an-ethical-future-for-brain-organoids-takes-shape-20200123/).

14 Huh D. et al. Reconstituting organ-level lung functions on a chip. Science. 2010; 328: 1662–1668.

15 McAleer C. W. et al. Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics. Science Translational Medicine. 2019; 11: eaav1386; Edington C. D. et al. Interconnected microphysiological systems for quantitative biology and pharmacology studies. Sci. Rep. 2018; 8: 1–18.

Глава 9. Экосистема внутри вас

1 Sender R. et al. Revised estimates for the number of human and bacteria cells in the body. PLOS Biology. 2016; 14: e1002533.

2 Venter J. C. et al. Environmental genome shotgun sequencing of the Sargasso Sea. Science. 2004; 304: 66–74.

3 Schlomann B. H., Parthasarathy R. Timescales of gut microbiome dynamics. Current Opinion in Microbiology. 2019; 50: 56–63.

4 Durack J., Lynch S. V. The gut microbiome: Relationships with disease and opportunities for therapy. Journal of Experimental Medicine. 2019; 216: 20–40; Douglas A. E. Fundamentals of Microbiome Science: How Microbes Shape Animal Biology. Princeton, NJ: Princeton University Press, 2018; The Gut Microbiome in Health and Disease / Haller D. (ed.). Cham, Switzerland: Springer, 2018; Tremlett H. et al. The gut microbiome in human neurological disease: A review. Ann. Neurol. 2017; 81: 369–382; Griffiths J. A., Mazmanian S. K. Emerging evidence linking the gut microbiome to neurologic disorders. Genome Medicine. 2018; 10: 98.

5 Drew L. Microbiota: Reseeding the gut. Nature. 2016; 540: S109 – S112; van Nood E. et al. Duodenal infusion of donor feces for recurrent clostridium difficile. New England Journal of Medicine. 2013; 368: 407–415; Colman R. J., Rubin D. T. Fecal microbiota transplantation as therapy for inflammatory bowel disease: A systematic review and meta-analysis. J. Crohns Colitis. 2014; 8: 1569–1581.

6 Zmora N. et al. Personalized gut mucosal colonization resistance to empiric probiotics is associated with unique host and microbiome features. Cell. 2018; 174: 1388–1405.e21.

7 Round J. L., Mazmanian S. K. The gut microbiota shapes intestinal immune responses during health and disease. Nat. Rev. Immunol. 2009; 9: 313–323; Hooper L. V. et al. Interactions between the microbiota and the immune system. Science. 2012; 336: 1268–1273; Jones T. A., Guillemin K. Racing to stay put: How resident microbiota stimulate intestinal epithelial cell proliferation. Curr. Pathobiol. Rep. 2018; 6: 23–28.

8 Hill J. H. et al. A conserved bacterial protein induces pancreatic beta cell expansion during zebrafish development. eLife. 2016; 5: e20145.

9 Schwarzer M. et al. Lactobacillus plantarum strain maintains growth of infant mice during chronic undernutrition. Science. 2016; 351: 854–857.

10 Finucane M. M. et al. A taxonomic signature of obesity in the microbiome? Getting to the guts of the matter. PLoS ONE. 2014; 9: e84689; Sze M. A., Schloss P. D. Looking for a signal in the noise: Revisiting obesity and the microbiome. mBio. 2016; 7: e01018– e01016.

11 О заболеваемости холерой и ее лечении см. статьи на сайтах ВОЗ (https://www.who.int/news-room/fact-sheets/detail/cholera) и Центров по контролю и профилактике заболеваний США (https://www.cdc.gov/cholera/treatment/index.html).

12 Russell B. et al. Type VI secretion system effectors: Poisons with a purpose. Nat. Rev. Micro. 2014; 12: 137–148.

13 Об экспериментах с холерным вибрионом и его T6SS в моей лаборатории: Logan S. L. et al. The Vibrio cholerae type VI secretion system can modulate host intestinal mechanics to displace gut bacterial symbionts. Proc. Natl. Acad. Sci. 2018; 115: E3779 – E3787.

14 Wiles T. J. et al. Swimming motility of a gut bacterial symbiont promotes resistance to intestinal expulsion and enhances inflammation. PLOS Biology. 2020; 18: e3000661.

15 Kotula J. W. et al. Programmable bacteria detect and record an environmental signal in the mammalian gut. Proc. Natl. Acad. Sci. 2014; 111: 4838–4843.

16 Cremer J. et al. Effect of flow and peristaltic mixing on bacterial growth in a gut-like channel. Proc. Natl. Acad. Sci. 2016; 113: 11414–11419.

17 Shin W. et al. Human intestinal morphogenesis Controlled by Transepithelial Morphogen Gradient and Flow-Dependent Physical Cues in a microengineered gut-on-a-chip. iScience. 2019; 15: 391–406.

18 Goldford J. E. et al. Emergent simplicity in microbial community assembly. Science. 2018; 361: 469–474.

19 May R. M. Stability and Complexity in Model Ecosystems (reprint ed.). Princeton, NJ: Princeton University Press, 2001; May R. M. Will a large complex system be stable? Nature. 1972; 238: 413–414.

20 Cui W. et al. Diverse communities behave like typical random ecosystems. bioRxiv. 2019 (https://doi.org/10.1101/596551); Marsland III R. et al. Available energy fluxes drive a transition in the diversity, stability, and functional structure of microbial communities. PLOS Computational Biology. 2019; 15: e1006793.

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